Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 9/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9166681 | 0.88 | PIK3CD (0.41) | IDH1PARP1CD38CYP3A4PIK3CD | |
| L-697661 SCHEMBL599639 | 0.85 | FABP4 (0.34) | IDH1FABP4ALDH1A1GLA | |
| L-697661 SCHEMBL29456987 | 0.85 | FABP4 (0.34) | IDH1FABP4ALDH1A1GLA | |
| SCHEMBL9168366 | 0.83 | MTNR1A (0.37) | PARP1 | |
| SCHEMBL9281450 | 0.83 | RAB9A (0.41) | PIK3CDPIK3CB | |
| SCHEMBL9846224 | 0.82 | PARP1 (0.37) | PARP1PTGESPIK3CDPIK3CBPIK3CG | |
| SCHEMBL9846291 | 0.81 | PARP1 (0.35) | IDH1PARP1CD38CYP3A4PTGES | |
| SCHEMBL9171193 | 0.80 | FABP4 (0.34) | IDH1CD38CYP3A4FABP4 | |
| SCHEMBL29456981 | 0.78 | KMT2A (0.35) | ALDH1A1GLA | |
| SCHEMBL6367001 | 0.78 | KMT2A (0.35) | ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650362-A1 | ANTIVIRAL COMBINATIONS | GLAXO GROUP LIMITED (GB) | 1995-05-03 | — | — | EP | claimed |
| WO-1994002154-A1 | ANTIVIRAL COMBINATIONS | GLAXO GROUP LIMITED (GB) | 1994-02-03 | — | — | WO | claimed |
| EP-0577243-A2 | Recombinant human HIV-neutralizing monoclonal antibodies for prevention and treatment of HIV infection | MERCK & CO. INC. (US) | 1994-01-05 | — | — | EP | claimed |
| WO-1993019785-A1 | RECOMBINANT HUMAN HIV-NEUTRALIZING MONOCLONAL ANTIBODIES FOR PREVENTION AND TREATMENT OF HIV INFECTION | MERCK & CO., INC. (US) | 1993-10-14 | — | — | WO | claimed |
| EP-0484071-A2 | Synergism of HIV reverse transcriptase inhibitors | MERCK & CO. INC. (US) | 1992-05-06 | — | — | EP | claimed |
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | claimed |
| EP-0666744-A1 | USE OF BHAP COMPOUNDS IN COMBINATION WITH OTHER NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS FOR THE TREATMENT OF HIV INFECTION | THE UPJOHN COMPANY (US) | 1995-08-16 | — | — | EP | disclosed |
| EP-0650362-A1 | ANTIVIRAL COMBINATIONS | GLAXO GROUP LIMITED (GB) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994009781-A1 | USE OF BHAP COMPOUNDS IN COMBINATION WITH OTHER NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS FOR THE TREATMENT OF HIV INFECTION | THE UPJOHN COMPANY (US) | 1994-05-11 | — | — | WO | disclosed |
| WO-1994002154-A1 | ANTIVIRAL COMBINATIONS | GLAXO GROUP LIMITED (GB) | 1994-02-03 | — | — | WO | disclosed |
| EP-0577243-A2 | Recombinant human HIV-neutralizing monoclonal antibodies for prevention and treatment of HIV infection | MERCK & CO. INC. (US) | 1994-01-05 | — | — | EP | disclosed |
| WO-1993019785-A1 | RECOMBINANT HUMAN HIV-NEUTRALIZING MONOCLONAL ANTIBODIES FOR PREVENTION AND TREATMENT OF HIV INFECTION | MERCK & CO., INC. (US) | 1993-10-14 | — | — | WO | disclosed |
| EP-0484071-A2 | Synergism of HIV reverse transcriptase inhibitors | MERCK & CO. INC. (US) | 1992-05-06 | — | — | EP | disclosed |