Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9278111 | 0.89 | PIK3CD (0.44) | PIK3CDPIK3CBALDH1A1HPGDMEN1 | |
| SCHEMBL9846224 | 0.87 | PARP1 (0.37) | PIK3CDPIK3CBALDH1A1HPGDMEN1 | |
| SCHEMBL9680343 | 0.86 | PIK3CD (0.41) | PIK3CDPIK3CBALDH1A1HPGDMEN1 | |
| SCHEMBL9846101 | 0.84 | ALDH1A1 (0.38) | ALDH1A1HPGDMEN1KMT2AGLA | |
| SCHEMBL9280614 | 0.82 | PIK3CD (0.42) | PIK3CDPIK3CBALDH1A1HPGDMEN1 | |
| SCHEMBL9166681 | 0.82 | PIK3CD (0.41) | PIK3CDPIK3CBALDH1A1MEN1KMT2A | |
| SCHEMBL5573693 | 0.81 | MAPT (0.54) | PIK3CDPIK3CBMEN1KMT2ANPC1 | |
| SCHEMBL9283877 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HPGDMEN1KMT2AGLA | |
| SCHEMBL9280809 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HPGDMEN1KMT2AGLA | |
| SCHEMBL9281338 | 0.75 | PIK3CD (0.44) | PIK3CDPIK3CBALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | claimed |
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |