Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 5/20 | 0.41 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | DPYD | Q12882 | 1/20 | 0.37 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11832453 | 0.94 | CRHBP (0.47) | CRHBPCRHR2KDM4EALDH1A1HPGD | |
| SCHEMBL11833923 | 0.92 | CRHBP (0.46) | CRHBPCRHR2KDM4EALDH1A1HPGD | |
| SCHEMBL11839255 | 0.79 | CRHBP (0.43) | CRHBPCRHR2KDM4EALDH1A1HPGD | |
| SCHEMBL5117155 | 0.75 | CRHBP (0.54) | CRHBPCRHR2KDM4EALDH1A1HPGD | |
| SCHEMBL8885481 | 0.72 | CRHBP (0.51) | CRHBPCRHR2KDM4EALDH1A1HPGD | |
| SCHEMBL9341183 | 0.71 | CRHBP (0.50) | CRHBPCRHR2KDM4EALDH1A1HPGD | |
| SCHEMBL7378101 | 0.71 | CRHBP (0.50) | CRHBPCRHR2KDM4EALDH1A1HPGD | |
| SCHEMBL10750342 | 0.71 | CRHBP (0.50) | CRHBPCRHR2KDM4EALDH1A1HPGD | |
| SCHEMBL17844413 | 0.70 | KDM4E (0.47) | CRHBPCRHR2KDM4EALDH1A1HPGD | |
| SCHEMBL1258908 | 0.70 | CRHBP (0.49) | CRHBPCRHR2KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |