Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.37 |
| ▸ | GLB1 | P16278 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10849451 | 0.73 | MAPK1 (0.49) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL9846290 | 0.70 | GRIN2D (0.34) | MAPTGAA | |
| SCHEMBL9846085 | 0.70 | POLB (0.34) | ALDH1A1MAPTGAAPOLBKDM4E | |
| SCHEMBL19834811 | 0.69 | TSHR (0.47) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL18322320 | 0.68 | FUCA1 (0.49) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL13365129 | 0.68 | CYP4F2 (0.48) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL18322314 | 0.68 | FUCA1 (0.46) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL20414045 | 0.67 | TTR (0.57) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL18334195 | 0.67 | TTR (0.66) | ALDH1A1MAPTL3MBTL1LMNAGAA | |
| SCHEMBL9164330 | 0.65 | MAPT (0.41) | ALDH1A1MAPTL3MBTL1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |