Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846124 | 0.81 | RPS6KB1 (0.40) | POLBMAPTKDM4EGAAHPGD | |
| SCHEMBL9432629 | 0.78 | MEN1 (0.47) | MAPTKDM4EKMT2A | |
| SCHEMBL27337641 | 0.77 | POLB (0.49) | POLBMAPTKDM4EGAAHPGD | |
| SCHEMBL9278136 | 0.74 | MAPT (0.51) | POLBMAPTKDM4EGAAPDE3B | |
| SCHEMBL9283645 | 0.74 | MAPT (0.48) | POLBMAPTKDM4EGAAPDE3B | |
| SCHEMBL9168694 | 0.73 | PDE3B (0.42) | MAPTKDM4EGAAPDE3BPDE3A | |
| SCHEMBL9164330 | 0.73 | MAPT (0.41) | POLBMAPTKDM4EGAAHPGD | |
| SCHEMBL9170296 | 0.72 | KDM4E (0.44) | POLBMAPTKDM4EGAAPDE3B | |
| SCHEMBL9846165 | 0.72 | PDE3B (0.41) | MAPTKDM4EGAAPDE3BPDE3A | |
| SCHEMBL9846139 | 0.72 | CYP2C9 (0.37) | MAPTKDM4EGAAHCAR2PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |