SCHEMBL9846328

SCHEMBL9846328

CCCCc1cccnc1OC(OC)=C(C(=O)O)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SLC13A5 Q86YT5 4/20 0.38
CYP2C9 P11712 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TRPV1 Q8NER1 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
LMNA P02545 2/20 0.36
CYP1A2 P05177 1/20 0.36
TSHR P16473 1/20 0.36
CYP2C19 P33261 1/20 0.36
C3AR1 Q16581 1/20 0.35
PPARA Q07869 1/20 0.34
HTT P42858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9846387 0.75 TDP1 (0.49) ALDH1A1TDP1
SCHEMBL16057708 0.74 PPARA (0.48) SLC13A5PPARA
SCHEMBL16057138 0.74 PPARA (0.48) SLC13A5PPARA
SCHEMBL16057893 0.74 PPARA (0.48) SLC13A5PPARA
SCHEMBL16057099 0.74 PPARA (0.48) SLC13A5PPARA
SCHEMBL16057097 0.72 THRA (0.47) SLC13A5LMNAPPARA
SCHEMBL16057137 0.72 THRA (0.47) SLC13A5LMNAPPARA
SCHEMBL16057892 0.72 THRA (0.47) SLC13A5LMNAPPARA
SCHEMBL16057706 0.72 THRA (0.47) SLC13A5LMNAPPARA
SCHEMBL28054534 0.71 SLC13A5 (0.49) SLC13A5CYP2C9CYP3A4CYP2D6L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0415569-A2 Agrochemical compositions ZENECA LIMITED (GB) 1991-03-06 EP disclosed