SCHEMBL9846353

SCHEMBL9846353

CO/C=C(/C(=O)O)c1ccccc1CSC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
LMNA P02545 2/20 0.35
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CA4 P22748 1/20 0.33
CA7 P43166 1/20 0.33
GAA P10253 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
EGFR P00533 1/20 0.32
ERBB2 P04626 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.32
CYP2C9 P11712 1/20 0.32
HIF1A Q16665 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9846356 1.00 ALDH1A1 (0.35) ALDH1A1LMNACA12CA1CA2
SCHEMBL9846352 0.86 CYP1A2 (0.39) ALDH1A1PTGDR2
SCHEMBL9846354 0.86 CYP1A2 (0.39) ALDH1A1PTGDR2
SCHEMBL9846381 0.84 PPARG (0.32) ALDH1A1LMNACA12CA1CA2
SCHEMBL9846376 0.84 PPARG (0.32) ALDH1A1LMNACA12CA1CA2
SCHEMBL9846351 0.82 ALDH1A1 (0.40) ALDH1A1LMNAGAAL3MBTL1PTGDR2
SCHEMBL8814742 0.82 IDO1 (0.33) ALDH1A1LMNAPTGDR2HIF1A
SCHEMBL8814746 0.82 IDO1 (0.33) ALDH1A1LMNAPTGDR2HIF1A
SCHEMBL9846346 0.82 ALDH1A1 (0.40) ALDH1A1LMNAGAAL3MBTL1PTGDR2
SCHEMBL9846362 0.81 CYP1A2 (0.51) ALDH1A1LMNAL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0416746-A2 Fungicides containing an alkoxycarbonylvinyl group or an alkyloxyimino group AGREVO UK LIMITED (GB) 1991-03-13 EP disclosed