SCHEMBL9846354

SCHEMBL9846354

COC=C(C(=O)O)c1ccccc1CSC(=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 5/20 0.36
ALDH1A1 P00352 3/20 0.34
NPC1 O15118 1/20 0.34
GPR139 Q6DWJ6 1/20 0.34
MEN1 O00255 1/20 0.34
AKR1C1 Q04828 2/20 0.33
PTGDR2 Q9Y5Y4 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 1/20 0.33
AKT1 P31749 1/20 0.33
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9846352 1.00 CYP1A2 (0.39) CYP1A2CYP2C19KMT2AALDH1A1NPC1
SCHEMBL9846355 0.92 CYP1A2 (0.38) CYP1A2CYP2C19KMT2AALDH1A1NPC1
SCHEMBL9846358 0.92 CYP1A2 (0.51) CYP1A2CYP2C19ALDH1A1NPC1AKR1C1
SCHEMBL9846362 0.92 CYP1A2 (0.51) CYP1A2CYP2C19ALDH1A1NPC1AKR1C1
SCHEMBL9846415 0.92 NPC1 (0.41) CYP1A2CYP2C19KMT2AALDH1A1NPC1
SCHEMBL9846361 0.92 CYP1A2 (0.38) CYP1A2CYP2C19KMT2AALDH1A1NPC1
SCHEMBL9846414 0.92 NPC1 (0.41) CYP1A2CYP2C19KMT2AALDH1A1NPC1
SCHEMBL9846399 0.87 PTGS1 (0.36) CYP1A2CYP2C19KMT2AALDH1A1GPR139
SCHEMBL9846353 0.86 ALDH1A1 (0.35) ALDH1A1PTGDR2
SCHEMBL9846356 0.86 ALDH1A1 (0.35) ALDH1A1PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0416746-A2 Fungicides containing an alkoxycarbonylvinyl group or an alkyloxyimino group AGREVO UK LIMITED (GB) 1991-03-13 EP disclosed