SCHEMBL9846365

SCHEMBL9846365

CCCOCOC(Oc1ccccc1)=C(C(=O)O)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
MAPT P10636 4/20 0.42
KMT2A Q03164 3/20 0.42
ALDH1A1 P00352 3/20 0.42
MEN1 O00255 1/20 0.42
THRB P10828 1/20 0.42
HPGD P15428 1/20 0.42
ELANE P08246 4/20 0.38
KAT6A Q92794 1/20 0.36
FAAH O00519 5/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13415664 0.78 LMNA (0.46) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL6206065 0.75 TSHR (0.47) MAPTKMT2AALDH1A1ELANE
SCHEMBL6836606 0.75 LMNA (0.73) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL6204948 0.71 ELANE (0.51) LMNAMAPTKMT2AALDH1A1ELANE
SCHEMBL1145279 0.71 ELANE (0.51) LMNAMAPTKMT2AALDH1A1ELANE
SCHEMBL18812997 0.71 MEN1 (0.50) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL9487594 0.71 LMNA (0.49) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL9846357 0.69 KMT2A (0.41) LMNAMAPTKMT2AALDH1A1MEN1
SCHEMBL6204762 0.69 ELANE (0.53) MAPTKMT2AALDH1A1ELANE
SCHEMBL16732166 0.69 LMNA (0.46) LMNAMAPTKMT2AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0415569-A2 Agrochemical compositions ZENECA LIMITED (GB) 1991-03-06 EP disclosed