Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28760907 | 0.80 | TSHR (0.46) | MAPTGAASMN1; SMN2HTTTSHR | |
| SCHEMBL6206065 | 0.76 | TSHR (0.47) | MAPTGAASMN1; SMN2HTTTSHR | |
| SCHEMBL9846357 | 0.75 | KMT2A (0.41) | MAPTKAT6AGAASMN1; SMN2TSHR | |
| SCHEMBL9846384 | 0.70 | SMN1; SMN2 (0.38) | MAPTSMN1; SMN2HTTTSHRF2 | |
| SCHEMBL3018658 | 0.69 | F2 (0.59) | MAPTKAT6AHSD11B1SMN1; SMN2TSHR | |
| SCHEMBL3026705 | 0.69 | F2 (0.59) | MAPTKAT6AHSD11B1SMN1; SMN2TSHR | |
| SCHEMBL6206489 | 0.68 | NPC1 (0.45) | MAPTSMN1; SMN2HTTTSHRELANE | |
| SCHEMBL5974780 | 0.68 | F2 (0.57) | MAPTKAT6AHSD11B1SMN1; SMN2TSHR | |
| SCHEMBL6261808 | 0.67 | BCAT1 (0.43) | MAPTHSD11B1SMN1; SMN2HTTTSHR | |
| SCHEMBL3018681 | 0.67 | BCAT1 (0.43) | MAPTHSD11B1SMN1; SMN2HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415569-A2 | Agrochemical compositions | ZENECA LIMITED (GB) | 1991-03-06 | — | — | EP | claimed |