Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 5/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | F12 | P00748 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846325 | 0.79 | L3MBTL1 (0.41) | SMN1; SMN2LMNAHTTNPSR1KDM4E | |
| SCHEMBL9846273 | 0.74 | POLB (0.36) | LMNAHTTPOLBTDP1RAB9A | |
| SCHEMBL9846369 | 0.74 | KMT2A (0.33) | SMN1; SMN2LMNAHTTNPSR1MITF | |
| SCHEMBL28760907 | 0.72 | TSHR (0.46) | SMN1; SMN2HTTMAPTTDP1RAB9A | |
| SCHEMBL9846388 | 0.70 | KMT2A (0.38) | SMN1; SMN2LMNAHTTNPSR1KDM4E | |
| SCHEMBL9846395 | 0.70 | MAPT (0.39) | SMN1; SMN2HTTMAPTF2TSHR | |
| SCHEMBL9846357 | 0.68 | KMT2A (0.41) | SMN1; SMN2LMNAMAPTRAB9AALDH1A1 | |
| SCHEMBL6206065 | 0.68 | TSHR (0.47) | SMN1; SMN2HTTMAPTTDP1RAB9A | |
| SCHEMBL245065 | 0.67 | NPC1 (0.46) | SMN1; SMN2LMNAHTTOPRK1KDM4E | |
| SCHEMBL2829058 | 0.67 | LMNA (0.53) | SMN1; SMN2LMNAMITFKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415569-A2 | Agrochemical compositions | ZENECA LIMITED (GB) | 1991-03-06 | — | — | EP | claimed |