Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846413 | 1.00 | L3MBTL1 (0.39) | L3MBTL1ELANEPPARGPPARDPPARA | |
| SCHEMBL9338293 | 0.85 | L3MBTL1 (0.43) | L3MBTL1STAT3HTTSMN1; SMN2MEN1 | |
| SCHEMBL9336639 | 0.85 | L3MBTL1 (0.43) | L3MBTL1STAT3HTTSMN1; SMN2MEN1 | |
| SCHEMBL9846315 | 0.77 | L3MBTL1 (0.36) | L3MBTL1ELANESTAT3HTTSMN1; SMN2 | |
| SCHEMBL9846313 | 0.77 | L3MBTL1 (0.36) | L3MBTL1ELANESTAT3HTTSMN1; SMN2 | |
| SCHEMBL9680900 | 0.76 | HCAR2 (0.32) | HCAR2DHODH | |
| SCHEMBL9680902 | 0.76 | HCAR2 (0.32) | HCAR2DHODH | |
| SCHEMBL9681319 | 0.74 | DAGLA (0.34) | HCAR2 | |
| SCHEMBL9681317 | 0.74 | DAGLA (0.34) | HCAR2 | |
| SCHEMBL9338308 | 0.74 | L3MBTL1 (0.48) | L3MBTL1STAT3HTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0462800-A2 | Inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1991-12-27 | — | — | EP | disclosed |