Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 13/20 | 0.40 |
| ▸ | ATP4B | P51164 | 13/20 | 0.40 |
| ▸ | UTRN | P46939 | 2/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9336639 | 1.00 | L3MBTL1 (0.43) | L3MBTL1ATP4AATP4BUTRNSTAT3 | |
| SCHEMBL9449235 | 0.87 | ATP4A (0.40) | L3MBTL1ATP4AATP4BUTRNMEN1 | |
| SCHEMBL9449238 | 0.87 | ATP4A (0.40) | L3MBTL1ATP4AATP4BUTRNMEN1 | |
| SCHEMBL6954929 | 0.86 | L3MBTL1 (0.41) | L3MBTL1ATP4AATP4BUTRNSTAT3 | |
| SCHEMBL6954927 | 0.86 | L3MBTL1 (0.41) | L3MBTL1ATP4AATP4BUTRNSTAT3 | |
| SCHEMBL9846410 | 0.85 | L3MBTL1 (0.39) | L3MBTL1STAT3HTTSMN1; SMN2MEN1 | |
| SCHEMBL9846413 | 0.85 | L3MBTL1 (0.39) | L3MBTL1STAT3HTTSMN1; SMN2MEN1 | |
| SCHEMBL9336647 | 0.85 | ATP4A (0.41) | ATP4AATP4BUTRNMEN1NPC1 | |
| SCHEMBL9846142 | 0.84 | MEN1 (0.41) | L3MBTL1ATP4AATP4BUTRNSMN1; SMN2 | |
| SCHEMBL9846147 | 0.84 | MEN1 (0.41) | L3MBTL1ATP4AATP4BUTRNSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5290941-A | Synthesizing styrylbenzoxazoles; low temperature treatment with potassium tert-butoxide; reverse transcriptase inhibitor | MERCK & CO., INC. (US) | 1994-03-01 | — | — | US | disclosed |