SCHEMBL9846424

SCHEMBL9846424

O=C(O)OC1CN(c2ccccc2)C(=O)O1

nearest known ligand 0.50

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 18/20 0.50
FADS1 O60427 1/20 0.48
F10 P00742 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7461984 0.83 GRM2 (0.41) GRM2F10
SCHEMBL7466428 0.82 ITGB3 (0.46) GRM2F10
SCHEMBL5763612 0.81 GRM2 (0.53) GRM2FADS1
SCHEMBL7462745 0.80 ITGB3 (0.39) GRM2FADS1F10
SCHEMBL9846416 0.77 GRM2 (0.41) GRM2FADS1
SCHEMBL7461633 0.76 ITGB3 (0.51) F10
SCHEMBL7457619 0.76 PLK1 (0.43)
SCHEMBL4670666 0.76 GRM2 (0.54) GRM2FADS1F10
SCHEMBL4669702 0.76 GRM2 (0.54) GRM2FADS1F10
SCHEMBL2322579 0.76 GRM2 (0.54) GRM2FADS1F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0417044-A2 Oxazolidinones and thiones as plantgrowth regulators CIBA-GEIGY AG (CH) 1991-03-13 EP claimed
EP-0417044-A2 Oxazolidinones and thiones as plantgrowth regulators CIBA-GEIGY AG (CH) 1991-03-13 EP disclosed