SCHEMBL5763612

SCHEMBL5763612

COC1CN(c2ccccc2)C(=O)O1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 19/20 0.53
FADS1 O60427 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27573617 0.82 FADS1 (0.60) GRM2FADS1
SCHEMBL27573619 0.82 FADS1 (0.60) GRM2FADS1
SCHEMBL9846424 0.81 GRM2 (0.50) GRM2FADS1
SCHEMBL27468588 0.78 USP30 (0.46) GRM2FADS1
SCHEMBL27461343 0.78 FADS1 (0.43) GRM2FADS1
SCHEMBL27461345 0.78 FADS1 (0.43) GRM2FADS1
SCHEMBL6266797 0.77 GRM2 (0.57) GRM2FADS1
SCHEMBL6268966 0.76 GRM2 (0.72) GRM2
SCHEMBL28009037 0.74 FADS1 (0.41) GRM2FADS1
SCHEMBL28009036 0.74 FADS1 (0.41) GRM2FADS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7094900-B2 N-Aryl-2-oxazolidinones and their derivatives PHARMACIA & UPJOHN COMPANY LLC (US) 2006-08-22 US disclosed
EP-1539745-B1 N-ARYL-2-OXAZOLIDINONES AND THEIR DERIVATIVES PHARMACIA & UPJOHN CO LLC (US) 2006-03-29 EP disclosed
EP-1539745-A1 N-ARYL-2-OXAZOLIDINONES AND THEIR DERIVATIVES Pharmacia & Upjohn Company LLC (US) 2005-06-15 EP disclosed
US-20040072873-A1 N-Aryl-2-oxazolidinones and their derivatives GADWOOD ROBERT C (US) 2004-04-15 US disclosed
WO-2004014897-A1 N-ARYL-2-OXAZOLIDINONES AND THEIR DERIVATIVES PHARMACIA & UPJOHN COMPANY LLC (US) 2004-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040072873-A1 N-Aryl-2-oxazolidinones and their derivatives OXA1L, NDUFS7, NDUFS6 GRM2 4266/4885FADS1 2565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.