Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | HTR6 | P50406 | 1/20 | 0.57 |
| ▸ | ESRRG | P62508 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759290 | 0.87 | ESR1 (0.58) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL29375143 | 0.87 | ESR1 (0.58) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL9846556 | 0.85 | MEN1 (0.46) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL6751257 | 0.81 | ESR1 (0.46) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL23861352 | 0.79 | ESR1 (0.52) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL35973 | 0.78 | ESR1 (0.84) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| SCHEMBL6053109 | 0.76 | ESR1 (0.62) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| Bisphenol A SCHEMBL9774987 | 0.76 | ESR1 (1.00) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| Bisphenol A SCHEMBL15062 | 0.76 | ESR1 (1.00) | ESR1ESR2HSD17B10CYP3A4HPGD | |
| Bisphenol A SCHEMBL8058731 | 0.76 | ESR1 (1.00) | ESR1ESR2HSD17B10CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443820-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |