Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 10/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.45 |
| ▸ | ESRRG | P62508 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | ESRRB | O95718 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846448 | 0.85 | ESR1 (0.57) | MEN1KMT2AESR1ESR2ESRRG | |
| SCHEMBL3649608 | 0.80 | MEN1 (0.66) | MEN1KMT2AESR1ESR2ESRRG | |
| SCHEMBL3655939 | 0.77 | MEN1 (0.46) | MEN1KMT2AESR1ESR2ESRRG | |
| SCHEMBL3645147 | 0.77 | ESR1 (0.54) | MEN1KMT2AESR1ESR2ESRRG | |
| SCHEMBL3648165 | 0.77 | MEN1 (0.53) | MEN1KMT2AESR1ESR2ESRRG | |
| SCHEMBL23861352 | 0.75 | ESR1 (0.52) | KMT2AESR1ESR2CYP3A4HPGD | |
| SCHEMBL29375143 | 0.75 | ESR1 (0.58) | ESR1ESR2ESRRGLMNATYR | |
| SCHEMBL759290 | 0.75 | ESR1 (0.58) | ESR1ESR2ESRRGLMNATYR | |
| SCHEMBL3645152 | 0.75 | ESR1 (0.62) | MEN1KMT2AESR1ESR2ESRRG | |
| SCHEMBL7774227 | 0.74 | ESR1 (0.77) | MEN1KMT2AESR1ESR2ESRRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443820-A2 | Radiation-sensitive resin composition | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1991-08-28 | — | — | EP | disclosed |