Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.36 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL986113 | 0.99 | ACKR3 (0.41) | ACKR3ALKHTR4PTK2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL985798 | 0.93 | ACKR3 (0.38) | ACKR3ALKHTR4PTK2ALDH1A1 | |
| Tert-Butyl Formate SCHEMBL27823657 | 0.93 | SYK (0.36) | ACKR3ALKHTR4PTK2ALDH1A1 | |
| SCHEMBL981859 | 0.91 | SMYD3 (0.41) | ALDH1A1KMT2ABMPR1BBMPR1ATGFBR1 | |
| SCHEMBL984182 | 0.91 | SMYD3 (0.41) | ALDH1A1KMT2ABMPR1BBMPR1ATGFBR1 | |
| SCHEMBL985350 | 0.91 | CDK9 (0.41) | ALDH1A1KMT2AKDM5AKDM4CSCN8A | |
| SCHEMBL986391 | 0.91 | CDK9 (0.41) | ALDH1A1KMT2AKDM5AKDM4CSCN8A | |
| SCHEMBL983559 | 0.91 | PTK2 (0.39) | HTR4PTK2ALDH1A1KMT2AKDM1A | |
| SCHEMBL984894 | 0.90 | GRIN1 (0.36) | ALDH1A1KMT2ABMPR1BBMPR1ATGFBR1 | |
| SCHEMBL985885 | 0.90 | GRIN1 (0.36) | ALDH1A1KMT2ABMPR1BBMPR1ATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445501-B2 | Substituted 7-carboxamido-pyrrolo[3,2-d]pyrimidines | TAKEDA GMBH (DE) | 2013-05-21 | — | — | US | disclosed |
| US-20110021479-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | NYCOMED GMBH (DE) | 2011-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021479-A1 | PYRROLOPYRIMIDINECARBOXAMIDES | PDE5A, PDE3A, PDE2A | ACKR3 3933/4885ALK 1098/4885HTR4 1818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.