Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.30 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553666 | 0.76 | ERN1 (0.39) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL8553675 | 0.68 | ERN1 (0.38) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL9033065 | 0.68 | MEN1 (0.43) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL10838147 | 0.67 | ERN1 (0.75) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL9846472 | 0.67 | ERN1 (0.36) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL1300813 | 0.66 | ERN1 (0.59) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL10645211 | 0.65 | GPR35 (0.59) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL8125144 | 0.65 | ERN1 (0.51) | ERN1HTTLMNAMEN1KMT2A | |
| SCHEMBL8555674 | 0.64 | SMN1; SMN2 (0.33) | ERN1HTTLMNAALDH1A1MAPT | |
| SCHEMBL6978784 | 0.62 | MEN1 (0.55) | HTTLMNAMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411157-A1 | SPIROPYRAN COMPOUNDS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1991-02-06 | — | — | EP | disclosed |