Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.32 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553675 | 0.88 | ERN1 (0.38) | ERN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL9846467 | 0.81 | ERN1 (0.40) | ERN1ALDH1A1LMNAMAPTTHRB | |
| SCHEMBL8125146 | 0.78 | ERN1 (0.50) | ERN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL11025473 | 0.76 | ALDH1A1 (0.40) | ALDH1A1LMNAMAPTTHRBHTT | |
| SCHEMBL11023135 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTTHRBITGA4 | |
| SCHEMBL8553666 | 0.75 | ERN1 (0.39) | ERN1ALDH1A1LMNAMAPTHTT | |
| SCHEMBL11027638 | 0.75 | THRB (0.42) | ALDH1A1MAPTTHRBHTTMEN1 | |
| SCHEMBL11026162 | 0.73 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTTHRBMEN1 | |
| SCHEMBL11027009 | 0.73 | KMT2A (0.42) | ALDH1A1LMNAMAPTTHRBHTT | |
| SCHEMBL11028007 | 0.72 | THRB (0.42) | ALDH1A1LMNATHRBHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411157-A1 | SPIROPYRAN COMPOUNDS | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1991-02-06 | — | — | EP | disclosed |