Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9738795 | 0.91 | TSHR (0.34) | GAATSHRPOLBCCR2 | |
| SCHEMBL5210522 | 0.90 | CCR2 (0.35) | GAATSHRADRA2ANISCHPOLB | |
| SCHEMBL13051347 | 0.69 | ADRA2A (0.35) | GAATSHRADRA2ANISCHMEN1 | |
| SCHEMBL22288208 | 0.69 | KDM4E (0.31) | — | |
| SCHEMBL923787 | 0.68 | KDM4E (0.34) | TSHRADRA2ANISCH | |
| SCHEMBL19395652 | 0.67 | TSHR (0.34) | GAATSHRADRA2ANISCHMEN1 | |
| SCHEMBL2210415 | 0.66 | TSHR (0.37) | GAATSHRMEN1KMT2ATP53 | |
| SCHEMBL31145894 | 0.66 | — | — | |
| SCHEMBL19395640 | 0.66 | ADRA2A (0.33) | GAATSHRADRA2ANISCH | |
| SCHEMBL19395729 | 0.66 | ADRA2A (0.31) | GAATSHRADRA2ANISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411664-A2 | 2-(2-Vinylpyrrolidinylthio)carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-02-06 | — | — | EP | disclosed |