Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | BCL9 | O00512 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369987 | 0.87 | BCL9 (0.52) | HTR2ABCL9CTNNB1ALDH1A1MAPT | |
| SCHEMBL18631907 | 0.87 | BCL9 (0.52) | HTR2ABCL9CTNNB1ALDH1A1MAPT | |
| SCHEMBL9846626 | 0.87 | BCL9 (0.52) | HTR2ABCL9CTNNB1ALDH1A1MAPT | |
| SCHEMBL10062012 | 0.85 | HTR2A (0.56) | HTR2ABCL9CTNNB1ALDH1A1MAPT | |
| SCHEMBL22959846 | 0.85 | HTR2A (0.56) | HTR2ABCL9CTNNB1ALDH1A1MAPT | |
| SCHEMBL38661981 | 0.84 | ALDH1A1 (0.54) | BCL9CTNNB1ALDH1A1MAPTTDP1 | |
| SCHEMBL30864656 | 0.84 | BCL9 (0.49) | HTR2ABCL9CTNNB1ALDH1A1MAPT | |
| SCHEMBL26601519 | 0.84 | BCL9 (0.49) | HTR2ABCL9CTNNB1ALDH1A1MAPT | |
| SCHEMBL19246047 | 0.83 | HTR2A (0.49) | HTR2ABCL9CTNNB1ALDH1A1MAPT | |
| SCHEMBL27355955 | 0.82 | HTR2A (0.53) | HTR2ABCL9CTNNB1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429232-A1 | N-substituted derivatives of 3R,4R-ethyl-[(1-methyl-1H-imidazol-5-yl)methyl]-2-pyrrolidinone | ALLERGAN, INC. (US) | 1991-05-29 | — | — | EP | disclosed |