Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | BCL9 | O00512 | 1/20 | 0.53 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.45 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22959846 | 1.00 | HTR2A (0.56) | HTR2ABCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL763025 | 0.95 | HTR2A (0.57) | HTR2ABCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL21433828 | 0.93 | MGLL (0.62) | HTR2ABCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL3912666 | 0.93 | HTR2A (0.50) | HTR2ABCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL9846659 | 0.93 | MGLL (0.62) | HTR2ABCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL23115326 | 0.93 | HTR2A (0.50) | HTR2ABCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL21433889 | 0.93 | MGLL (0.62) | HTR2ABCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL20588849 | 0.93 | HTR2A (0.50) | HTR2ABCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL21433779 | 0.93 | MGLL (0.62) | HTR2ABCL9CTNNB1MAPTL3MBTL1 | |
| SCHEMBL21777065 | 0.93 | MGLL (0.62) | HTR2ABCL9CTNNB1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021024039-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF PAIN AND DEPENDANCE DISORDERS | RIPPLE THERAPEUTICS CORPORATION (CA) | 2021-02-11 | — | — | WO | disclosed |
| US-9062160-B1 | Catalyst-free methods of forming polyurethanes from pentafluorophenyl carbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-06-23 | — | — | US | disclosed |
| US-9062160-B1 | Catalyst-free methods of forming polyurethanes from pentafluorophenyl carbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-06-23 | — | — | US | disclosed |
| US-9062160-B1 | Catalyst-free methods of forming polyurethanes from pentafluorophenyl carbonates | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2015-06-23 | — | — | US | disclosed |
| US-8137700-B2 | Main chain acid-degradable polymers for the delivery of bioactive materials | U.S. DEPARTMENT OF ENERGY (US) | 2012-03-20 | — | — | US | disclosed |
| US-20090220615-A1 | Main Chain Acid-Degradable Polymers for the Delivery of Bioactive Materials | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090220615-A1 | Main Chain Acid-Degradable Polymers for the Delivery of Bioactive Materials | CTSA, GAA, CTSB | HTR2A 4460/4885BCL9 2681/4885CTNNB1 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.