Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 7/20 | 0.69 |
| ▸ | AGTR2 | P50052 | 7/20 | 0.69 |
| ▸ | PPARG | P37231 | 4/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846690 | 0.83 | AGTR1 (0.65) | AGTR1AGTR2PPARG | |
| SCHEMBL7021447 | 0.82 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9846728 | 0.81 | AGTR1 (0.67) | AGTR1AGTR2PPARG | |
| SCHEMBL8393637 | 0.80 | PPARG (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9198204 | 0.79 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9196687 | 0.78 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL8393642 | 0.76 | AGTR1 (0.80) | AGTR1AGTR2PPARG | |
| SCHEMBL8790347 | 0.76 | AGTR1 (0.73) | AGTR1AGTR2PPARG | |
| SCHEMBL8396958 | 0.76 | PPARG (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL8396480 | 0.76 | AGTR1 (0.80) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |