Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.67 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.67 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | BRS3 | P32247 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846708 | 0.91 | AGTR1 (0.54) | AGTR1AGTR2PPARGFFAR1 | |
| SCHEMBL9846795 | 0.85 | AGTR1 (0.48) | AGTR1AGTR2PPARGFFAR1 | |
| SCHEMBL9846714 | 0.83 | AGTR1 (0.47) | AGTR1AGTR2PPARGFFAR1 | |
| SCHEMBL9846721 | 0.82 | AGTR1 (0.64) | AGTR1AGTR2BRS3 | |
| SCHEMBL9846768 | 0.81 | AGTR1 (0.69) | AGTR1AGTR2PPARG | |
| SCHEMBL27317908 | 0.81 | AGTR1 (1.00) | AGTR1AGTR2 | |
| SCHEMBL9846764 | 0.80 | AGTR1 (0.62) | AGTR1AGTR2BRS3 | |
| SCHEMBL9309923 | 0.80 | AGTR1 (0.67) | AGTR1AGTR2 | |
| SCHEMBL9309933 | 0.80 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9846705 | 0.79 | AGTR1 (0.43) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |