Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.67 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.67 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.62 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.62 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.62 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.59 |
| ▸ | ECE1 | P42892 | 1/20 | 0.57 |
| ▸ | ANPEP | P15144 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.55 |
| ▸ | ITGAV | P06756 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.54 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.54 |
| ▸ | TGM2 | P21980 | 4/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509765 | 0.92 | CPB1 (0.70) | CPB1CPB2SIRT2SIRT1SIRT3 | |
| Lysine SCHEMBL10720682 | 0.89 | ITGB3 (0.60) | CPB1CPB2SIRT2SIRT1SIRT3 | |
| SCHEMBL8179347 | 0.88 | CPB1 (0.74) | CPB1CPB2SIRT2SIRT1SIRT3 | |
| SCHEMBL287475 | 0.88 | ITGB3 (0.66) | CPB1CPB2SIRT2SIRT1SIRT3 | |
| SCHEMBL15968143 | 0.88 | ITGB3 (0.66) | CPB1CPB2SIRT2SIRT1SIRT3 | |
| SCHEMBL287474 | 0.88 | ITGB3 (0.66) | CPB1CPB2SIRT2SIRT1SIRT3 | |
| SCHEMBL6476819 | 0.88 | ITGB3 (0.66) | CPB1CPB2SIRT2SIRT1SIRT3 | |
| SCHEMBL29733071 | 0.87 | ITGB3 (0.65) | CPB1CPB2SIRT2SIRT1SIRT3 | |
| Hydrochloric Acid SCHEMBL21219335 | 0.87 | ITGB3 (0.65) | CPB1CPB2SIRT2SIRT1SIRT3 | |
| Hydrochloric Acid SCHEMBL11310715 | 0.87 | ITGB3 (0.65) | CPB1CPB2SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434979-A1 | Peptide derivatives useful as antagonists of bombesin and gastrin-releasing peptide | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-07-03 | — | — | EP | disclosed |