Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.40 |
| ▸ | AGT | P01019 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846790 | 0.85 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9846789 | 0.84 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9310870 | 0.83 | AGTR1 (0.65) | AGTR1AGTR2AGT | |
| SCHEMBL9846782 | 0.83 | AGTR1 (0.43) | AGTR1AGTR2 | |
| SCHEMBL9218501 | 0.80 | CCNB2 (0.37) | AGTR1 | |
| SCHEMBL9308989 | 0.79 | AGTR1 (0.64) | AGTR1AGTR2 | |
| SCHEMBL9309669 | 0.79 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9846726 | 0.78 | CCNB2 (0.39) | AGTR1 | |
| SCHEMBL9311372 | 0.78 | AGTR1 (0.59) | AGTR1AGTR2 | |
| SCHEMBL9308860 | 0.77 | AGTR1 (0.63) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |