Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 8/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9846726 | 0.89 | CCNB2 (0.39) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL9661962 | 0.80 | CCNB2 (0.39) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL9846804 | 0.80 | AGTR1 (0.45) | AGTR1 | |
| SCHEMBL9661956 | 0.77 | CCNB2 (0.37) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL9846675 | 0.76 | CCNB2 (0.42) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL9846776 | 0.75 | CCNB2 (0.42) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL8545582 | 0.73 | AGTR1 (0.39) | AGTR1 | |
| SCHEMBL8545586 | 0.73 | AGTR1 (0.38) | AGTR1 | |
| SCHEMBL9177078 | 0.70 | AGTR1 (0.39) | AGTR1POLB | |
| SCHEMBL9311241 | 0.69 | AGTR1 (0.35) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520724-B1 | Angiotensin II antagonists | ZENECA LTD (GB) | 1995-09-20 | — | — | EP | disclosed |
| US-5281613-A | Heterocyclic ring substituted benzofuran, benzothiofuran, or indole derivative | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-01-25 | — | — | US | disclosed |
| EP-0429257-A2 | Indole derivatives | GLAXO GROUP LIMITED (GB) | 1991-05-29 | — | — | EP | disclosed |