Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNG | P07510 | 1/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | CHRND | Q07001 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9369724 | 0.90 | DRD2 (0.40) | FAAHMGLLNCOA3OPRL1OPRM1 | |
| SCHEMBL1255944 | 0.88 | OPRL1 (0.52) | OPRL1OPRM1OPRK1HRH3OPRD1 | |
| SCHEMBL6344006 | 0.82 | SLC6A2 (0.52) | OPRL1OPRM1OPRK1DRD2DRD4 | |
| SCHEMBL20010952 | 0.80 | OPRL1 (0.42) | OPRL1OPRM1OPRK1DRD2DRD4 | |
| SCHEMBL6348944 | 0.80 | SLC6A2 (0.55) | OPRL1OPRM1OPRK1DRD2DRD4 | |
| SCHEMBL14516443 | 0.79 | HRH3 (0.41) | OPRL1OPRM1OPRK1HRH3HDAC1 | |
| SCHEMBL28416538 | 0.79 | CYP11B2 (0.49) | ALOX5 | |
| SCHEMBL19615271 | 0.78 | ESR2 (0.45) | DRD2DRD4DRD3HRH3MAPT | |
| SCHEMBL3900447 | 0.77 | DRD2 (0.61) | OPRL1OPRM1OPRK1DRD2DRD4 | |
| SCHEMBL17186803 | 0.76 | DRD2 (0.60) | OPRL1OPRM1OPRK1DRD2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410661-A2 | Bicyclic derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-30 | — | — | EP | disclosed |