Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | ANPEP | P15144 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771627 | 1.00 | MMP2 (0.49) | MMP2ANPEPPOLBALDH1A1MAPT | |
| SCHEMBL9847239 | 1.00 | MMP2 (0.49) | MMP2ANPEPPOLBALDH1A1MAPT | |
| SCHEMBL8691622 | 1.00 | MMP2 (0.49) | MMP2ANPEPPOLBALDH1A1MAPT | |
| SCHEMBL6778186 | 0.92 | TDP1 (0.48) | MMP2ANPEPPOLBALDH1A1MAPT | |
| SCHEMBL9728361 | 0.92 | TDP1 (0.48) | MMP2ANPEPPOLBALDH1A1MAPT | |
| SCHEMBL19177149 | 0.90 | ALDH1A1 (0.48) | MMP2ANPEPALDH1A1MAPTHPGD | |
| SCHEMBL17447371 | 0.90 | ALDH1A1 (0.48) | MMP2ANPEPALDH1A1MAPTHPGD | |
| SCHEMBL9205704 | 0.90 | GAA (0.48) | POLBALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9199841 | 0.90 | GAA (0.48) | POLBALDH1A1MAPTHPGDTDP1 | |
| SCHEMBL9727808 | 0.90 | GAA (0.48) | POLBALDH1A1MAPTHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435320-A1 | 2(2-Cyclopropylpyrrolidin-4-ylthio)-carbapenem derivatives | Banyu Pharmaceutical Co., Ltd. (JP) | 1991-07-03 | — | — | EP | disclosed |