Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172788 | 0.69 | AOC3 (0.38) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL2036346 | 0.68 | AOC3 (0.37) | AOC3NPC1RAB9AALDH1A1SLC6A4 | |
| SCHEMBL28750379 | 0.68 | ADRA1A (0.43) | AOC3ALDH1A1PYGLPYGM | |
| SCHEMBL11884403 | 0.68 | AR (0.49) | AOC3AURKAKDRNPC1RAB9A | |
| SCHEMBL73543 | 0.68 | AOC3 (0.47) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL21408185 | 0.67 | KDR (0.47) | AURKAKDRPDGFRBFGFR1FLT3 | |
| SCHEMBL7481839 | 0.67 | FLT3 (0.37) | AOC3AURKAKDRNPC1RAB9A | |
| SCHEMBL5803120 | 0.67 | KDM4E (0.40) | AURKANPC1RAB9AFGFR1FLT3 | |
| SCHEMBL5667289 | 0.67 | AOC3 (0.36) | AOC3NPC1RAB9ALOXL2FLT3 | |
| SCHEMBL6691603 | 0.67 | PRCP (0.53) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0431856-A2 | Heterocyclic compounds | ZENECA LIMITED (GB) | 1991-06-12 | — | — | EP | claimed |