Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21992975 | 0.71 | — | — | |
| 2,5-Thiophenenedicarboxaldehyde SCHEMBL178830 | 0.67 | — | — | |
| SCHEMBL3053124 | 0.66 | ALDH1A1 (0.41) | ALDH1A1GAAKMT2AKDM4EDPP4 | |
| SCHEMBL8178817 | 0.65 | ALDH1A1 (0.43) | ALDH1A1GAASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL2742437 | 0.64 | KDM4E (0.32) | ALDH1A1KDM4E | |
| SCHEMBL16888821 | 0.63 | ALDH1A1 (0.39) | ALDH1A1GAAKDM4EDPP4CYP2C9 | |
| SCHEMBL40949 | 0.62 | — | — | |
| SCHEMBL11075658 | 0.62 | ALDH1A1 (0.42) | ALDH1A1RAB9ASMN1; SMN2KMT2AKDM4E | |
| SCHEMBL14266834 | 0.61 | KDM4E (0.34) | ALDH1A1GAAHSD17B10SMN1; SMN2KMT2A | |
| SCHEMBL278904 | 0.61 | DPP4 (0.65) | ALDH1A1GAAKMT2AKDM4EDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0429999-A1 | Novel cephalosporins, process for their preparation and their use as medicaments | BAYER AG (DE) | 1991-06-05 | — | — | EP | disclosed |