SCHEMBL7750651

SCHEMBL7750651

CCCCOCCCC(O)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.45
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
HTT P42858 2/20 0.36
MEN1 O00255 1/20 0.36
THRB P10828 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPT P10636 1/20 0.36
USP2 O75604 1/20 0.36
CYP3A4 P08684 2/20 0.35
CETP P11597 1/20 0.33
PLA2G2C Q5R387 2/20 0.33
SPHK1 Q9NYA1 1/20 0.33
PKM P14618 1/20 0.32
FAAH O00519 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7750656 1.00 TSHR (0.45) TSHRCES2CES1HTTMEN1
SCHEMBL7754322 0.94 TSHR (0.43) TSHRCES2CES1HTTMEN1
SCHEMBL7754324 0.94 TSHR (0.43) TSHRCES2CES1HTTMEN1
SCHEMBL7750659 0.92 HSD17B10 (0.39) TSHRCES2CES1HTTMEN1
SCHEMBL7750662 0.92 HSD17B10 (0.39) TSHRCES2CES1HTTMEN1
SCHEMBL14534599 0.92 TSHR (0.45) TSHRCES2CES1HTTMEN1
SCHEMBL7750647 0.86 USP2 (0.39) TSHRCES2CES1HTTMEN1
SCHEMBL7750639 0.86 USP2 (0.39) TSHRCES2CES1HTTMEN1
SCHEMBL7754277 0.86 ALDH1A1 (0.36) TSHRCES2CES1CETPPKM
SCHEMBL7634968 0.86 ALDH1A1 (0.36) TSHRCES2CES1CETPPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0737733-B1 Liquid crystal compound having ferrielectric phase and liquid crystal composition MITSUBISHI GAS CHEMICAL CO (JP) 2001-02-21 EP disclosed
US-5728864-A AROMATIC DIESTERS FOR INJECTION BETWEEN SUBSTRATES FOR LIQUID CRYSTAL DISPLAYS MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-03-17 US disclosed
EP-0737733-A1 Liquid crystal compound having ferrielectric phase and liquid crystal composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1996-10-16 EP disclosed