Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 2/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16706324 | 0.91 | MAPT (0.81) | MAPTMMP14CRHBPCRHR2ALDH1A1 | |
| SCHEMBL13226534 | 0.89 | MAPT (0.74) | MAPTPTGS2NPC1RAB9AAPP | |
| SCHEMBL9097274 | 0.89 | MAPT (0.74) | MAPTPTGS2NPC1RAB9AAPP | |
| SCHEMBL9097270 | 0.89 | MAPT (0.74) | MAPTPTGS2NPC1RAB9AAPP | |
| SCHEMBL9847298 | 0.88 | MAPT (0.58) | MAPTPTGS2NPC1RAB9AAPP | |
| SCHEMBL3038695 | 0.87 | MAPT (0.57) | MAPTPTGS2NPC1RAB9AAPP | |
| SCHEMBL3038698 | 0.87 | MAPT (0.57) | MAPTPTGS2NPC1RAB9AAPP | |
| SCHEMBL9362626 | 0.86 | PTGS2 (0.55) | MAPTPTGS2NPC1RAB9AAPP | |
| SCHEMBL9362623 | 0.86 | PTGS2 (0.55) | MAPTPTGS2NPC1RAB9AAPP | |
| SCHEMBL8905957 | 0.83 | MAPT (0.53) | MAPTPTGS2NPC1RAB9AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0406888-A2 | Nonlinear optical polymer composition and method for producing the same | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1991-01-09 | — | — | EP | disclosed |