Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SORD | Q00796 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9029494 | 0.87 | SMN1; SMN2 (0.52) | HRH4MAPTHRH1HTTSMN1; SMN2 | |
| SCHEMBL16238117 | 0.83 | PIK3CA (0.56) | LMNAPIK3CDPIK3CAPIK3CBHTT | |
| SCHEMBL1136912 | 0.79 | AKT2 (0.47) | HRH4HTR3APIK3CBTSHRMEN1 | |
| SCHEMBL22924653 | 0.78 | HRH4 (0.59) | HRH4HTR3AALDH1A1HSD17B10USP2 | |
| SCHEMBL2523906 | 0.76 | MAPK1 (0.53) | LMNAPIK3CDPIK3CAPIK3CBHTT | |
| SCHEMBL4316997 | 0.76 | TSHR (0.59) | LMNAPIK3CDPIK3CAPIK3CBHTT | |
| SCHEMBL22924655 | 0.75 | HRH4 (0.52) | HRH4HTR3ALMNAHTTSMN1; SMN2 | |
| SCHEMBL10456578 | 0.74 | ALDH1A1 (0.45) | HRH4MAPTHRH1SMN1; SMN2ALDH1A1 | |
| SCHEMBL434846 | 0.73 | POLB (0.55) | LMNAPIK3CDPIK3CAPIK3CBHRH1 | |
| SCHEMBL8981922 | 0.72 | HRH4 (0.51) | HRH4HTR3AMAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419890-A2 | Stable pharmaceutical formulations for antineoplastic compounds having more than one ethyleneimine group, and method | AMERICAN CYANAMID COMPANY (US) | 1991-04-03 | — | — | EP | disclosed |