SCHEMBL9847419

SCHEMBL9847419

Nc1ccc(N)c(S(=O)(=O)CCl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
RECQL P46063 3/20 0.46
CYP3A4 P08684 3/20 0.46
THRB P10828 2/20 0.46
ALOX15 P16050 2/20 0.46
TSHR P16473 2/20 0.46
HPGD P15428 1/20 0.46
CASP1 P29466 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PKM P14618 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
HTR6 P50406 1/20 0.37
GAA P10253 3/20 0.35
CDC25B P30305 1/20 0.35
RAPGEF4 Q8WZA2 1/20 0.35
TDP1 Q9NUW8 3/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
POLB P06746 2/20 0.34
MAPT P10636 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17774699 0.82 GAA (0.50) ALDH1A1RECQLCYP3A4THRBALOX15
SCHEMBL9877386 0.77 CA2 (0.54) ALDH1A1RECQLCYP3A4THRBALOX15
SCHEMBL9294471 0.76 CDC25B (0.55) ALDH1A1RECQLCYP3A4THRBALOX15
SCHEMBL17459909 0.76 ALDH1A1 (0.38) ALDH1A1RECQLCYP3A4THRBALOX15
SCHEMBL10630409 0.76 ALDH1A1 (0.40) ALDH1A1RECQLCYP3A4THRBALOX15
SCHEMBL11407296 0.75 GAA (0.58) CYP3A4ALOX15TSHRCASP1HTR6
SCHEMBL3653053 0.74 TSHR (0.47) ALDH1A1RECQLCYP3A4TSHRHPGD
SCHEMBL393315 0.74 CA2 (0.54) ALDH1A1RECQLCYP3A4THRBALOX15
SCHEMBL31095544 0.74 CA2 (0.54) ALDH1A1RECQLCYP3A4THRBALOX15
SCHEMBL115254 0.72 ALDH1A1 (0.55) ALDH1A1RECQLCYP3A4THRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0458746-A1 Azo dyes, process for their preparation and the use thereof CIBA-GEIGY AG (CH) 1991-11-27 EP disclosed