Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847569 | 0.92 | MTNR1B (0.37) | MTNR1BHPGDSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9754850 | 0.89 | MTNR1B (0.38) | MTNR1BHPGDSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9847572 | 0.86 | MEN1 (0.38) | MTNR1BHPGDSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9847576 | 0.85 | MEN1 (0.40) | MTNR1BHPGDSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9847547 | 0.84 | PPARA (0.42) | MTNR1BHPGDSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9847543 | 0.80 | ALDH1A1 (0.42) | HPGDSMN1; SMN2TSHRPOLBTDP1 | |
| SCHEMBL9847560 | 0.78 | MEN1 (0.38) | MTNR1BHPGDSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL9847530 | 0.77 | CYP3A4 (0.33) | RXRARXRBRXRG | |
| SCHEMBL67099 | 0.75 | MEN1 (0.43) | MTNR1BHPGDSMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL29390499 | 0.75 | MEN1 (0.43) | MTNR1BHPGDSMN1; SMN2TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0434074-A2 | Process for the production of 1-lower alkoxy-1-lower alkyl-3-substituted phenylurea, and intermediate thereof and process for the production of the intermediate | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1991-06-26 | — | — | EP | disclosed |