SCHEMBL9847644

SCHEMBL9847644

CON(C)C(=O)Nc1ccc(Oc2ccc3c(c2)OC(C)(OC)CC3)cc1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
PKM P14618 1/20 0.43
RAB9A P51151 1/20 0.43
PPARG P37231 11/20 0.39
PPARA Q07869 11/20 0.39
PPARD Q03181 1/20 0.38
NPY5R Q15761 2/20 0.36
MTNR1A P48039 1/20 0.35
MTNR1B P49286 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847645 0.90 PPARA (0.40) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL9847611 0.90 MEN1 (0.40) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL9847575 0.85 PPARG (0.40) MEN1KMT2ARAB9APPARGPPARA
SCHEMBL9847581 0.85 PPARG (0.43) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL67099 0.84 MEN1 (0.43) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL29390499 0.84 MEN1 (0.43) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL9847564 0.80 MEN1 (0.41) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL9847597 0.80 MEN1 (0.41) MEN1KMT2ATDP1PKMRAB9A
Metobromuron SCHEMBL15994323 0.80 KMT2A (0.52) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL9749284 0.80 SCN9A (0.43) PPARGPPARAPPARDNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434074-A2 Process for the production of 1-lower alkoxy-1-lower alkyl-3-substituted phenylurea, and intermediate thereof and process for the production of the intermediate MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-06-26 EP disclosed