SCHEMBL9847645

SCHEMBL9847645

CCOC1(C)CCc2ccc(Oc3ccc(NC(=O)N(C)OC)cc3)cc2O1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 16/20 0.40
PPARG P37231 15/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
PKM P14618 1/20 0.40
RAB9A P51151 1/20 0.40
PPARD Q03181 2/20 0.38
NPY5R Q15761 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847644 0.90 MEN1 (0.43) PPARAPPARGMEN1KMT2ATDP1
SCHEMBL9847611 0.87 MEN1 (0.40) PPARAPPARGMEN1KMT2ATDP1
SCHEMBL9847547 0.85 PPARA (0.42) PPARAPPARGTDP1PPARD
SCHEMBL9847576 0.85 MEN1 (0.40) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL9847581 0.84 PPARG (0.43) PPARAPPARGMEN1KMT2ATDP1
SCHEMBL9847560 0.78 MEN1 (0.38) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL9847605 0.77 ALDH1A1 (0.42) PPARAPPARGPPARD
SCHEMBL9749284 0.77 SCN9A (0.43) PPARAPPARGPPARDNPY5R
SCHEMBL67099 0.77 MEN1 (0.43) MEN1KMT2ATDP1PKMRAB9A
SCHEMBL29390499 0.77 MEN1 (0.43) MEN1KMT2ATDP1PKMRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434074-A2 Process for the production of 1-lower alkoxy-1-lower alkyl-3-substituted phenylurea, and intermediate thereof and process for the production of the intermediate MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-06-26 EP disclosed