SCHEMBL9749284

SCHEMBL9749284

CN(C)C(=O)Nc1ccc(Oc2ccc3c(c2)OC(C)(C)CC3)cc1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 2/20 0.43
PPARG P37231 7/20 0.41
PPARA Q07869 7/20 0.41
ABHD6 Q9BV23 2/20 0.41
DAGLA Q9Y4D2 2/20 0.41
PPARD Q03181 1/20 0.40
NPY5R Q15761 1/20 0.40
EPHX2 P34913 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847644 0.80 MEN1 (0.43) PPARGPPARAPPARDNPY5R
SCHEMBL9847645 0.77 PPARA (0.40) PPARGPPARAPPARDNPY5R
SCHEMBL9847611 0.77 MEN1 (0.40) PPARGPPARAPPARDNPY5R
SCHEMBL9749356 0.76 ALDH1A1 (0.48) PPARGPPARAABHD6DAGLAPPARD
SCHEMBL9847581 0.75 PPARG (0.43) PPARGPPARANPY5R
SCHEMBL9749398 0.75 RAB9A (0.45) PPARGPPARAABHD6DAGLAPPARD
SCHEMBL9847575 0.75 PPARG (0.40) PPARGPPARAPPARD
SCHEMBL5048965 0.74 CYP1A2 (0.50)
SCHEMBL9749254 0.73 PPARG (0.39) SCN9APPARGPPARAABHD6DAGLA
SCHEMBL9847547 0.72 PPARA (0.42) PPARGPPARAPPARDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0230475-B1 NOVEL UREA DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF AND HERBICIDE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-03-18 EP disclosed
US-4838924-A NONPHYTOTOXIC MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-06-13 US disclosed