SCHEMBL9847771

SCHEMBL9847771

NC1c2ccccc2-c2c(-c3ccccc3)cccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
HSD17B10 Q99714 2/20 0.40
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38
HTR2A P28223 1/20 0.38
DPP4 P27487 1/20 0.36
HNF4A P41235 1/20 0.36
HTR2C P28335 1/20 0.36
MAPK1 P28482 2/20 0.35
HPGD P15428 1/20 0.35
BCL2L1 Q07817 1/20 0.35
CYP2A6 P11509 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
BCAT2 O15382 1/20 0.34
TP53 P04637 1/20 0.34
RAB9A P51151 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL21382703 0.81 ALDH1A1 (0.45) ALDH1A1HSD17B10HTR2ADPP4MAPK1
SCHEMBL3798577 0.80 PDK2 (0.42) HTR2ACYP2A6HTR7HTR2B
SCHEMBL28187238 0.78 ALDH1A1 (0.43) ALDH1A1HSD17B10CHRNB2CHRNA4DPP4
SCHEMBL15366509 0.78 ADORA2A (0.44) ALDH1A1HSD17B10HTR2ADPP4HPGD
SCHEMBL9847767 0.77 ALDH1A1 (0.42) ALDH1A1HSD17B10CHRNB2CHRNA4DPP4
SCHEMBL28010330 0.77 PDCD1 (0.35) ALDH1A1HSD17B10CHRNB2CHRNA4DPP4
SCHEMBL2605016 0.76 KDM1A (0.41) ALDH1A1HTR2AHTR2CMAPK1HTR7
SCHEMBL11592270 0.76 CHRNB2 (0.38) ALDH1A1HSD17B10CHRNB2CHRNA4DPP4
SCHEMBL28107581 0.76 ALDH1A1 (0.36) ALDH1A1HSD17B10CHRNB2CHRNA4HTR2A
SCHEMBL3552319 0.76 ALDH1A1 (0.51) ALDH1A1HSD17B10HNF4AMAPK1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0412882-A1 Gas separation membrane Institut Français du Pétrole (FR) 1991-02-13 EP disclosed