Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847878 | 0.90 | MAPT (0.42) | MAPTGLAGAAHCAR3ALDH1A1 | |
| SCHEMBL10530485 | 0.88 | MAPT (0.41) | MAPTGLAGAAHCAR3ALDH1A1 | |
| SCHEMBL25217733 | 0.87 | HCAR3 (0.39) | MAPTGLAGAAHCAR3ALDH1A1 | |
| SCHEMBL30461558 | 0.87 | HCAR3 (0.39) | MAPTGLAGAAHCAR3ALDH1A1 | |
| SCHEMBL9847906 | 0.86 | MAPT (0.44) | MAPTGLAGAAHCAR3ALDH1A1 | |
| SCHEMBL9847925 | 0.86 | HCAR3 (0.41) | MAPTGLAGAAHCAR3ALDH1A1 | |
| SCHEMBL25220217 | 0.78 | TDP1 (0.42) | MAPTGLAGAAHCAR3ALDH1A1 | |
| SCHEMBL20337755 | 0.77 | MAPT (0.47) | MAPTGLAGAAHCAR3ALDH1A1 | |
| SCHEMBL2217900 | 0.75 | MAPT (0.51) | MAPTGLAGAAHCAR3ALDH1A1 | |
| SCHEMBL2507487 | 0.74 | MAPT (0.44) | MAPTGLAGAAHCAR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | claimed |
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | disclosed |