Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847878 | 0.87 | MAPT (0.42) | HCAR3MAPTGLAGAAALDH1A1 | |
| SCHEMBL9847822 | 0.86 | MAPT (0.41) | HCAR3MAPTGLAGAAALDH1A1 | |
| SCHEMBL10530485 | 0.83 | MAPT (0.41) | HCAR3MAPTGLAGAAALDH1A1 | |
| SCHEMBL9847906 | 0.78 | MAPT (0.44) | HCAR3MAPTGLAGAAALDH1A1 | |
| SCHEMBL25217733 | 0.76 | HCAR3 (0.39) | HCAR3MAPTGLAGAAALDH1A1 | |
| SCHEMBL30461558 | 0.76 | HCAR3 (0.39) | HCAR3MAPTGLAGAAALDH1A1 | |
| SCHEMBL2217900 | 0.72 | MAPT (0.51) | HCAR3MAPTGLAGAAALDH1A1 | |
| SCHEMBL17896593 | 0.71 | MAPT (0.56) | HCAR3MAPTGLAGAAALDH1A1 | |
| SCHEMBL29525723 | 0.71 | MAPT (0.56) | HCAR3MAPTGLAGAAALDH1A1 | |
| SCHEMBL14296999 | 0.70 | HCAR3 (0.39) | HCAR3MAPTGLAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | claimed |