Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.47 |
| ▸ | GPR4 | P46093 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8566867 | 0.92 | AGTR2 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9847882 | 0.91 | AGTR1 (0.48) | AGTR1AGTR2GPR4PPARG | |
| SCHEMBL9847847 | 0.90 | AGTR1 (0.47) | AGTR1AGTR2GPR4PPARG | |
| SCHEMBL9847838 | 0.89 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL8741166 | 0.86 | AGTR2 (0.61) | AGTR1AGTR2GPR4PPARG | |
| SCHEMBL9847826 | 0.85 | AGTR1 (0.62) | AGTR1AGTR2GPR4 | |
| SCHEMBL9847830 | 0.84 | AGTR1 (0.53) | AGTR1AGTR2GPR4PPARG | |
| SCHEMBL683358 | 0.83 | AGTR2 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9089289 | 0.82 | AGTR1 (0.42) | AGTR1AGTR2GPR4 | |
| SCHEMBL8563844 | 0.81 | AGTR2 (0.53) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | claimed |
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | disclosed |