SCHEMBL9847852

SCHEMBL9847852

CCOc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2)c(C(=O)O)c1

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 3/20 0.51
AGTR2 P50052 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9847923 0.93 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL683364 0.91 AGTR1 (0.59) AGTR1AGTR2
SCHEMBL9847855 0.90 AGTR1 (0.46) AGTR1AGTR2
SCHEMBL9847864 0.89 AGTR1 (0.58) AGTR1AGTR2
SCHEMBL8972103 0.84 AGTR1 (0.53) AGTR1AGTR2
SCHEMBL8566014 0.82 AGTR1 (0.54) AGTR1AGTR2
SCHEMBL9847799 0.81 AGTR1 (0.56) AGTR1AGTR2
SCHEMBL9847882 0.81 AGTR1 (0.48) AGTR1AGTR2
SCHEMBL9847805 0.81 AGTR1 (0.63) AGTR1AGTR2
SCHEMBL9847850 0.80 AGTR1 (0.59) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0420237-A1 Biphenylmethane derivative, the use of it and pharmacological compositions containing same Eisai Co., Ltd. (JP) 1991-04-03 EP claimed