Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.58 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847799 | 0.93 | AGTR1 (0.56) | AGTR1AGTR2PPARGMME | |
| SCHEMBL9847850 | 0.91 | AGTR1 (0.59) | AGTR1AGTR2PPARG | |
| SCHEMBL8564718 | 0.90 | AGTR1 (0.70) | AGTR1AGTR2PPARGMME | |
| SCHEMBL9847852 | 0.89 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL9847804 | 0.87 | AGTR1 (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL9847808 | 0.85 | AGTR2 (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL9847839 | 0.85 | PPARG (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL9847874 | 0.84 | AGTR1 (0.55) | AGTR1AGTR2PPARG | |
| SCHEMBL8559430 | 0.83 | AGTR1 (0.68) | AGTR1AGTR2PPARGMME | |
| SCHEMBL8958505 | 0.82 | AGTR1 (0.81) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | claimed |