Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.71 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.71 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958505 | 0.91 | AGTR1 (0.81) | AGTR1AGTR2NOS1NOS2PPARG | |
| SCHEMBL8802161 | 0.90 | AGTR1 (0.82) | AGTR1AGTR2PPARG | |
| SCHEMBL685515 | 0.83 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL30838455 | 0.83 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL20017271 | 0.81 | AGTR1 (0.80) | AGTR1AGTR2NOS1NOS2PPARG | |
| SCHEMBL8972527 | 0.80 | AGTR1 (0.93) | AGTR1AGTR2NOS1NOS2PPARG | |
| SCHEMBL9847805 | 0.79 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL20860208 | 0.79 | AGTR1 (0.82) | AGTR1AGTR2NOS1NOS2PPARG | |
| SCHEMBL8872682 | 0.79 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL9847837 | 0.79 | AGTR1 (0.58) | AGTR1AGTR2NOS1NOS2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | disclosed |