Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.81 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.81 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9847862 | 0.91 | AGTR1 (0.71) | AGTR1AGTR2NOS1NOS2PPARG | |
| SCHEMBL20017271 | 0.90 | AGTR1 (0.80) | AGTR1AGTR2NOS1NOS2PPARG | |
| SCHEMBL30838455 | 0.90 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL685515 | 0.90 | AGTR1 (1.00) | AGTR1AGTR2PPARG | |
| SCHEMBL9847805 | 0.88 | AGTR1 (0.63) | AGTR1AGTR2 | |
| SCHEMBL8972527 | 0.86 | AGTR1 (0.93) | AGTR1AGTR2NOS1NOS2PPARG | |
| SCHEMBL9847827 | 0.85 | AGTR2 (0.69) | AGTR1AGTR2NOS1NOS2PPARG | |
| SCHEMBL9847808 | 0.85 | AGTR2 (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL9847804 | 0.84 | AGTR1 (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL8800937 | 0.84 | AGTR1 (0.79) | AGTR1AGTR2NOS1NOS2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559236-A | Intermediates for substituted biphenylmethylmidazopyridine angiotensin II antagonists | EISAI CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |