Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27956814 | 0.82 | ALDH1A1 (0.48) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL38662525 | 0.81 | TSHR (0.53) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL31711442 | 0.80 | GRIN2D (0.47) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL4246480 | 0.79 | ALDH1A1 (0.48) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL194903 | 0.78 | PKM (0.43) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL8596722 | 0.76 | TSHR (0.60) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL27843142 | 0.76 | TSHR (0.45) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL935588 | 0.75 | GRIN2D (0.47) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL18925687 | 0.75 | GRIN2D (0.44) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1675773 | 0.74 | TSHR (0.42) | ALDH1A1TSHRGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | disclosed |