Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RORC | P51449 | 11/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10378209 | 0.76 | MAPT (0.44) | GPR174ALDH1A1MAPTRORCKDM4E | |
| SCHEMBL10375746 | 0.73 | GFER (0.58) | GPR174ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL9847870 | 0.73 | ALDH1A1 (0.43) | ALDH1A1MAPTKDM4E | |
| SCHEMBL13453977 | 0.70 | SMN1; SMN2 (0.69) | ALDH1A1MAPTKDM4E | |
| SCHEMBL9523467 | 0.68 | ALDH1A1 (0.44) | GPR174ALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL18711276 | 0.67 | TP53 (0.56) | GPR174ALDH1A1MAPTTP53 | |
| SCHEMBL9437309 | 0.67 | ACACB (0.39) | RORC | |
| SCHEMBL13419194 | 0.66 | MAPT (0.54) | GPR174ALDH1A1MAPT | |
| SCHEMBL29002632 | 0.66 | CHRM2 (0.48) | MAPTKDM4E | |
| SCHEMBL31485198 | 0.65 | ALDH1A1 (0.64) | GPR174ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430847-A1 | Procedure for the preparation of N-cyclopropyl-4-fluoroanilines | CENTRO MARGA PARA LA INVESTIGACION S.A. (ES) | 1991-06-05 | — | — | EP | disclosed |